Subgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variants

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URI
http://hdl.handle.net/20.500.14066/4728
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Author(s)
Su, Maxwell; Ping, Sara; Nguyen, Phuong-Vi; Rojas Segovia, Alejandra MaríaCONACYT Authority; Hussaini, Laila; Registre Carmola, Ludy; Taz, Azmain; Sullivan, Julie; Martin, Greg S.; Piantadosi, Anne; Martínez Pereira, Iara MagalyCONACYT Authority; Lam, Wilbur A.; Anderson, Evan J.; Waggoner, Jesse J.
Date of publishing
2022-11-10
Type of publication
info:eu-repo/semantics/article
Subject(s)
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subgenomic RNA (sgRNA) may indicate actively replicating virus, but sgRNA abundance has not been systematically compared between SARS-CoV-2 variants. sgRNA was quantified in 169 clinical samples by real-time reverse-transcription polymerase chain reaction, demonstrating similar relative abundance among known variants. Thus, sgRNA detection can identify individuals with active viral replication regardless of variant.
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Atribución/Reconocimiento-NoComercial-SinDerivados 4.0 Internacional
Except where otherwise noted, this item's license is described as Atribución/Reconocimiento-NoComercial-SinDerivados 4.0 Internacional