RT info:eu-repo/semantics/article
T1 Human Papillomavirus (HPV) infection and risk behavior in vaccinated and non-vaccinated paraguayan young women
A1 Bobadilla Frizzola, María Liz
A1 Villagra, Veronica
A1 Castro, Héctor
A1 Von-Horoch, Marta
A1 Araya, Soraya Angela Lorenza
A1 Deluca, Gerardo
A1 Salete de Paula, Vanessa
A2 Ministerio de Salud Pública y Bienestar Social. Laboratorio Central de Salud Pública
AB Cervical cancer is a global health concern and ranks fourth among the most prevalent cancers in women worldwide. Human papillomavirus (HPV) infection is a known precursor of cervical cancer and preventive measures include prophylactic vaccines. This study focused on sexually active Paraguayan women aged 18–25 years, exploring the intersection of HPV vaccination and sexual behavior. Among 254 participants, 40.9% received the Gardasil-4 vaccine, with no significant differences in sexual behavior between the vaccinated and unvaccinated sexually active groups. However, a notable decrease in the prevalence of HPV among the vaccinated women highlights the efficacy of this vaccine in reducing infections. The prevalence of any HPV type was 37.5% in vaccinated participants compared to 56.7% in unvaccinated participants (p = 0.0026). High-risk HPV types showed a significant difference, with a prevalence of 26.0% in vaccinated women compared with 52.7% in unvaccinated women (p < 0.001). Although a potential decline in genital warts was observed among the vaccinated individuals, statistical significance (p = 0.0564) was not reached. Despite the challenges in achieving high vaccination coverage, the observed reduction in HPV prevalence underscores the importance of ongoing monitoring, healthcare professional recommendations, and comprehensive risk management. These findings contribute to dispelling concerns about HPV vaccination influencing sexual behavior, advocating further large-scale research to explore the impact of vaccines on various HPV types and potential cross-protection.
PB Multidisciplinary Digital Publishing Institute
YR 2024
FD 2024-02-27
LK http://hdl.handle.net/20.500.14066/4406
UL http://hdl.handle.net/20.500.14066/4406
LA eng
NO Bobadilla, M. L., Villagra, V., Castro, H., von Horoch, M., Araya, S., Deluca, G., & Salete de Paula, V. (2024). Human Papillomavirus (HPV) Infection and Risk Behavior in Vaccinated and Non-Vaccinated Paraguayan Young Women. Pathogens, 13(3), 209. https://doi.org/10.3390/pathogens 13030209
NO Correspondence: bobadillaml@gmail.com
NO This article belongs to the Special Issue Latest Advances in Human Papillomavirus (HPV) Research.
NO Consejo Nacional de Ciencia y Tecnología
DS MINDS@UW
RD 03-nov-2024