RT info:eu-repo/semantics/article
T1 Dynamics of Triatoma infestans populations in the Paraguayan Chaco : population genetic analysis of household reinfestation following vector control
A1 Rojas de Arias, Gladys Antonieta
A1 Messenger, Louisa Alexandra
A1 Rolón, Miriam Soledad
A1 Vega Gómez, María Celeste
A1 Acosta, Nidia
A1 Villalba, Cesia
A1 Marcet, Paula L.
AB Background. Although domestic infestations by Triatoma infestans have been successfully controlled across Latin America, in areas of the Gran Chaco region, recurrent post-spraying house colonization continues to be a significant challenge, jeopardizing Chagas disease vector control and maintaining active Trypanosoma cruzi transmission.Methodology/Principal findings. To investigate the dynamics of triatomine reinfestation in a rural area of the Paraguayan Chaco, genetic characterization (based on 10 microsatellite loci and cytochrome B sequence polymorphisms) was performed on baseline and reinfestant T. infestans (n = 138) from four indigenous communities and adjacent sylvatic sites. House quality and basic economic activities were assessed across the four communities. Significant genetic differentiation was detected among all baseline triatomine populations. Faster reinfestation was observed in the communities with higher infestation rates pre-spraying. Baseline and reinfestant populations from the same communities were not genetically different, but two potentially distinct processes of reinfestation were evident. In Campo Largo, the reinfestant population was likely founded by domestic survivor foci, with reduced genetic diversity relative to the baseline population. However, in 12 de Junio, reinfestant bugs were likely derived from different sources, including survivors from the pre-spraying population and sympatric sylvatic bugs, indicative of gene-flow between these habitats, likely driven by high human mobility and economic activities in adjacent sylvatic areas.Conclusions/Significance. Our results demonstrate that sylvatic T. infestans threatens vector control strategies, either as a reinfestation source or by providing a temporary refuge during insecticide spraying. Passive anthropogenic importation of T. infestans and active human interactions with neighboring forested areas also played a role in recolonization. Optimization of spraying, integrated community development and close monitoring of sylvatic areas should be considered when implementing vector control activities in the Gran Chaco.
PB Public Library of Science
YR 2022
FD 2022-02-10
LK http://hdl.handle.net/20.500.14066/4427
UL http://hdl.handle.net/20.500.14066/4427
LA eng
NO Rojas de Arias, A., Messenger, L. A., Rolon, M., Vega, M. C., Acosta, N., Villalba, C., & Marcet, P. L. (2022). Dynamics of Triatoma infestans populations in the Paraguayan Chaco: Population genetic analysis of household reinfestation following vector control. PLOS ONE, 17(2), Artículo e0263465. https://doi.org/10.1371/journal.pone.0263465
NO Correspondence: Gladys Antonieta Rojas de Arias, rojasdearias@gmail.com
NO Consejo Nacional de Ciencia y Tecnología
DS MINDS@UW
RD 23-nov-2024