TY - JOUR AU - Fernández-Calleja, Vanessa AU - Fernández Nestosa, María José AU - Hernández, Pablo AU - Schvartzman, Jorge Bernardo AU - Krimer, Dora AU - Universidad Nacional de Asunción - Facultad Politécnica PY - 2019 UR - http://hdl.handle.net/20.500.14066/3848 AB - Wiskott-Aldrich syndrome (WAS) is a recessive X-linked inmmunodeficiency caused by loss-of-function mutations in the gene encoding the WAS protein (WASp). WASp plays an important role in the polymerization of the actin cytoskeleton in hematopoietic... LA - eng KW - 7 Salud KW - WISKOTT-ALDRICH KW - ERYTHROLEUKEMIA CELLS KW - ACTIN CYTOSKELETON KW - CRISPR/CAS9 KW - BRUTON TYROSINE KINASE TI - CRISPR/Cas9-mediated deletion of the Wiskott-Aldrich syndrome locus causes actin cytoskeleton disorganization in murine erythroleukemia cells DO - http://doi.org/10.7717/peerj.6284 T2 - PeerJ VL - 7 ER -