RT info:eu-repo/semantics/article
T1 SIR-SI model with a Gaussian transmission rate : understanding the dynamics of dengue outbreaks in Lima, Peru
A1 Ramírez Soto, Max Carlos
A1 Bogado Machuca, Juan Vicente
A1 Stalder Díaz, Diego Herbin
A1 Champin, Denisse
A1 Mártinez Fernández, María G.
A1 Schaerer Serra, Christian Emilio
AB Introduction. Dengue is transmitted by the Aedes aegypti mosquito as a vector, and a recent outbreak was reported in several districts of Lima, Peru. We conducted a modeling study to explain the transmission dynamics of dengue in three of these districts according to the demographics and climatology.Methodology. We used the weekly distribution of dengue cases in the Comas, Lurigancho, and Puente Piedra districts, as well as the temperature data to investigate the transmission dynamics. We used maximum likelihood minimization and the human susceptible-infected-recovered and vector susceptible-infected (SIR-SI) model with a Gaussian function for the infectious rate to consider external non-modeled variables.Results/principal findings. We found that the adjusted SIR-SI model with the Gaussian transmission rate (for modelling the exogenous variables) captured the behavior of the dengue outbreak in the selected districts. The model explained that the transmission behavior had a strong dependence on the weather, cultural, and demographic variables while other variables determined the start of the outbreak.Conclusion/significance. The experimental results showed good agreement with the data and model results when a Bayesian-Gaussian transmission rate was employed. The effect of weather was also observed, and a strong qualitative relationship was obtained between the transmission rate and computed effective reproduction number Rt.
PB Public Library of Science
YR 2023
FD 2023-04-13
LK http://hdl.handle.net/20.500.14066/4425
UL http://hdl.handle.net/20.500.14066/4425
LA eng
NO Ramírez Soto, M. C., Machuca, J. V. B., Stalder, D. H., Champin, D., Mártinez Fernández, M. G., & Schaerer, C. E. (2023). SIR-SI model with a Gaussian transmission rate: Understanding the dynamics of dengue outbreaks in Lima, Peru. PLOS ONE, 18(4), e0284263.https://doi.org/10.1371/journal.pone.0284263
NO Correspondence: Max Carlos Ramírez Soto. maxcrs22@gmail.com, c20330@utp.edu.pe
NO Consejo Nacional de Ciencia y Tecnología
DS MINDS@UW
RD 14-jul-2024