RT info:eu-repo/semantics/article
T1 Phytochemical and pharmacological aspects of the genus Chamaecrista : a systematic review
A1 Villalba Fariña, Domitila
A1 Escobar Ávalos, Melissa Mariel
A1 Cazal Martínez, Cinthia Carolina
A1 Barúa Chamorro, Javier Enrique
A1 de Oliveira Pereira, Fillipe
A1 Moura Mendes Arrúa, Juliana
A2 Universidad Nacional de Asunción. Centro Multidisciplinario de Investigaciones Tecnológicas
AB The genus Chamaecrista, belonging to the family Fabaceae, is mainly distributed in the American continent and is of great interest because of its extensive use in traditional medicine. This article presents a systematic review of the pharmacological and chemical properties of the Chamaecrista. Articles published between 2004 and 2023 were grouped through searches in the following databases: PubMed, SciELO, Scopus, Science Direct, Web of Science, and Google Scholar. Articles were included based on the selection and classification of titles and abstracts if they indicated the country of origin of the studies, plant species studied, compounds identified, and associated pharmacological activities. The results showed that most of the studies conducted in Brazil represented 35% of the published works. Moreover, Chamaecrista nictitans and Chamaecrista duckeana have been the most studied for their pharmacological potential, especially for their antioxidant activity. In addition, flavonoids were the leading group described, obtained from different extracts of various parts of the plant, with leaves being the most utilized. Despite promising advances in understanding the chemical composition and pharmacological properties of the genus Chamaecrista, this review highlights that no preclinical in vivo and clinical studies have been reported. This study underscores the importance of continuing research to identify and isolate new bioactive molecules from this genus, aiming to elucidate their pharmacological functions and potential therapeutic applications.
PB Open Science Publishers LLP
YR 2025
FD 2025-12-05
LK http://hdl.handle.net/20.500.14066/4711
UL http://hdl.handle.net/20.500.14066/4711
LA eng
NO Villalba, D., Escobar, M., Cazal Martínez, C., Barúa, J. E., De Oliveira Pereira, F, & Moura Mendes, J. (2025). Phytochemical and pharmacological aspects of the genus Chamaecrista: a systematic review. Journal of Applied Pharmaceutical Science, 16(01), 005-028.https://doi.org/10.7324/JAPS.2025.241066
NO Corresponding Author: Juliana Moura-Mendes, Multidisciplinary Center for Technological Research, National University of Asunción, San Lorenzo, Paraguay. E-mail: jmendes@rec.una.py.
NO Consejo Nacional de Ciencia y Tecnología
DS MINDS@UW
RD 03-sep-2026