RT info:eu-repo/semantics/article
T1 Subgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variants
A1 Su, Maxwell
A1 Ping, Sara
A1 Nguyen, Phuong-Vi
A1 Rojas Segovia, Alejandra María
A1 Hussaini, Laila
A1 Registre Carmola, Ludy
A1 Taz, Azmain
A1 Sullivan, Julie
A1 Martin, Greg S.
A1 Piantadosi, Anne
A1 Martínez Pereira, Iara Magaly
A1 Lam, Wilbur A.
A1 Anderson, Evan J.
A1 Waggoner, Jesse J.
A2 Centro de Estudios y Formación para el Ecodesarrollo
AB Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subgenomic RNA (sgRNA) may indicate actively replicating virus, but sgRNA abundance has not been systematically compared between SARS-CoV-2 variants. sgRNA was quantified in 169 clinical samples by real-time reverse-transcription polymerase chain reaction, demonstrating similar relative abundance among known variants. Thus, sgRNA detection can identify individuals with active viral replication regardless of variant.
PB Oxford University Press
YR 2022
FD 2022-11-10
LK http://hdl.handle.net/20.500.14066/4728
UL http://hdl.handle.net/20.500.14066/4728
LA eng
NO Su, M., Ping, S., Nguyen, P., Rojas, A., Hussaini, L., Registre Carmola, L., Taz, A., Sullivan, J., Martin, G. S., Piantadosi, A., Martinez, M., Lam, W. A., Anderson, E. J., & Waggoner, J. J. (2022). Subgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variants. Open Forum Infectious Diseases, 9(11), Article ofac619. https://doi.org/10.1093/ofid/ofac619
NO Correspondence: Jesse J. Waggoner, MD, 1760 Haygood Drive NE, Room E-169, Bay E-1, Atlanta, GA 30322 (jjwaggo@emory.edu).
NO Consejo Nacional de Ciencia y Tecnología
DS MINDS@UW
RD 03-sep-2026