TY  - JOUR 
AU  - Fernández Calleja, Vanessa
AU  - Fernández de Nestosa, María José
AU  - Hernández, Pablo
AU  - Schvartzman, Jorge Bernardo
AU  - Krimer, Dora B.
AU  - Universidad Nacional de Asunción. Facultad Politécnica
PY  - 2019
UR  - http://hdl.handle.net/20.500.14066/3848
AB  - Wiskott-Aldrich syndrome (WAS) is a recessive X-linked inmmunodeficiency caused by loss-of-function mutations in the gene encoding the WAS protein (WASp). WASp plays an important role in the polymerization of the actin cytoskeleton in hematopoietic...
LA  - eng
PB  - PeerJ, Inc.
KW  - Hematology
KW  - Molecular Biology
KW  - 7. Salud
KW  - 7.3. Prevención, vigilancia y control de enfermedades transmisibles y no transmisibles
KW  - Actin cytoskeleton
KW  - Bruton tyrosine kinase
KW  - CRISPR/Cas9
KW  - Erythroleukemia cells
KW  - Wiskott-Aldrich
TI  - CRISPR/Cas9-mediated deletion of the Wiskott-Aldrich syndrome locus causes actin cytoskeleton disorganization in murine erythroleukemia cells
DO  - 10.7717/peerj.6284
T2  - PeerJ
VL  - 7
ER  -