TY - GEN AU - Martínez, Víctor AU - Schaerer Serra, Christian Emilio AU - Hernández, Pablo AU - Krimer, Dora B. AU - Schvartzman, Jorge Bernardo AU - Fernández de Nestosa, María José A4 - Universidad Nacional de Asunción. Facultad Politécnica PY - 2020 SN - 0739-1102 UR - http://hdl.handle.net/20.500.14066/3851 AB - DNA topology changes continuously as replication proceeds. Unwinding of the DNA duplex by helicases is favored by negative supercoiling but it causes the progressive accumulation of positive supercoiling ahead of the fork. This torsional stress must... LA - eng KW - 7. Salud KW - 7.3. Prevención, vigilancia y control de enfermedades transmisibles y no transmisibles KW - DNA topology KW - Pre-catenation metropolis Monte Carlo KW - Replication KW - Supercoiling TI - Distribution of torsional stress between the un-replicated and replicated regions in partially replicated molecules DO - 10.1080/07391102.2020.1751294 ER -