TY  - GEN 
AU  - Meyer, Michael J.
AU  - Lapcevic, Ryan
AU  - Romero, Alfonso E.
AU  - Yoon, Mark
AU  - Das, Jishnu
AU  - Beltrán, Juan Felipe
AU  - Mort, Matthew
AU  - Stenson, Peter D.
AU  - Cooper, David N.
AU  - Paccanaro, Alberto
AU  - Yu, Haiyuan
A4  - Universidad Católica Nuestra Señora de la Asunción
PY  - 2016
UR  - http://hdl.handle.net/20.500.14066/2830
AB  - A new algorithm and Web server, mutation3D (http://mutation3d.org), proposes driver genes in cancer by identifying clusters of amino acid substitutions within tertiary protein structures. We demonstrate the feasibility of using a 3D clustering...
LA  - eng
PB  - John Wiley & Sons Ltd.
KW  - 6. Producción y tecnología industrial
KW  - 6.16. Manufacture of basic pharmaceutical products and pharmaceutical preparations
KW  - Cancer
KW  - Clustering
KW  - Protein structures
KW  - Somatic mutations
KW  - Web tool
TI  - mutation3D: cancer gene prediction through atomic clustering of coding variants in the structural proteome
DO  - 10.1002/humu.22963
VL  - 37
ER  -