TY  - GEN 
AU  - Pertino, Mariano Walter
AU  - Carreño González, Patricio
AU  - Venegas González, Camila
AU  - Schmeda Hirschmann, Guillermo
AU  - Vega Gómez, María Celeste
AU  - Rolón, Miriam Soledad
AU  - Rojas de Arias, Gladys Antonieta
PY  - 2026
UR  - http://hdl.handle.net/20.500.14066/4793
AB  - Background/Objectives: Jatrophone is a bioactive diterpenoid with reported antitrypanosomal activity; however, its development as a lead compound is limited by pronounced cytotoxicity toward mammalian cells. This study aimed to explore the structural...
LA  - eng
PB  - Multidisciplinary Digital Publishing Institute
KW  - Antiprotozoal activity
KW  - Click chemistry
KW  - Jatrophone
KW  - Triazole hybrids
KW  - Trypanosoma cruzi
TI  - Triazole-functionalized jatrophone derivatives as antiprotozoal agents against Trypanosoma cruzi : synthesis, biological evaluation and structure—activity relationships
DO  - 10.3390/ph19050801
VL  - 19
ER  -