Evaluation of the genotoxic potential of a thiosemicarbazone derived from pregnenolone by the micronucleus test in mouse bone marrow. MU0009

Abstract

The results indicate that the thiosemicarbazone derived from pregnenolone shows no genotoxic effect in mouse bone marrow in a 48 h treatment. These results are very promising in the validation process of this compound as an antiparasitic agent.