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Molecular profile in Paraguayan colorectal cancer patients, towards to a precision medicine strategy

dc.contributor.authorFleitas, Tania 
dc.contributor.authorMartinez Ciarpaglini, Carolina
dc.contributor.authorAyala, Josefina
dc.contributor.authorGauna, Cinthia
dc.contributor.authorDenis, Rita Mabel Concepción
dc.contributor.authorYoffe, Ita 
dc.contributor.authorSforza, Silvia 
dc.contributor.authorMartínez de Filártiga Filártiga, María Teresa 
dc.contributor.authorPomata, Alicia
dc.contributor.authorIbarrola‐Villava, Maider
dc.contributor.authorArevshatyan, Sipan
dc.contributor.authorBurriel, Verónica
dc.contributor.authorBoscá, Diego
dc.contributor.authorPastor, Oscar
dc.contributor.authorFerrer, Ana
dc.contributor.authorCarrasco, Francisca
dc.contributor.authorMongort, Cristina
dc.contributor.authorNavarro, Samuel
dc.contributor.authorRibas, Gloria
dc.contributor.authorCervantes, Andres
dc.contributor.otherLaboratorio Curie S.R.L. (PY)es
dc.date.accessioned2022-04-27T00:25:19Z
dc.date.available2022-04-27T00:25:19Z
dc.date.issued2019
dc.identifier.urihttp://hdl.handle.net/20.500.14066/3656
dc.description.abstractSomatic mutation analysis and evaluation of microsatellite instability (MSI) have become mandatory for selecting personalized therapy strategies for advanced colorectal cancer and are not available as routine methods in Paraguay. The aims of this study were to analyze the molecular profile as well as the microsatellite status in a series of advanced colorectal patients from two public hospitals from Paraguay, to introduce these methodologies in the routine practice to guide the therapeutic decisions.es
dc.description.sponsorshipCONACYT – Consejo Nacional de Ciencia y Tecnologíaes
dc.language.isoenges
dc.subject.classification7 Saludes
dc.subject.otherCOLORECTAL CANCERes
dc.subject.otherMICROSATELLITE INSTABILITYes
dc.subject.otherMUTATIONAL PROFILEes
dc.subject.otherONCOCARTAes
dc.subject.otherPRECISION MEDICINEes
dc.titleMolecular profile in Paraguayan colorectal cancer patients, towards to a precision medicine strategyes
dc.typeresearch articlees
dc.identifier.doi10.1002/cam4.2191es
dc.description.fundingtextPROCIENCIAes
dc.journal.titleCancer Medicinees
dc.page.initial1es
dc.page.final11es
dc.relation.projectCONACYTPINV15-156es
dc.rights.accessRightsopen accesses
dc.rights.copyright© 2019 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.es
dc.subject.ocdeCANCERes


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