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Subgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variants

dc.contributor.authorSu, Maxwell
dc.contributor.authorPing, Sara
dc.contributor.authorNguyen, Phuong-Vi
dc.contributor.authorRojas Segovia, Alejandra María 
dc.contributor.authorHussaini, Laila
dc.contributor.authorRegistre Carmola, Ludy
dc.contributor.authorTaz, Azmain
dc.contributor.authorSullivan, Julie
dc.contributor.authorMartin, Greg S.
dc.contributor.authorPiantadosi, Anne
dc.contributor.authorMartínez Pereira, Iara Magaly 
dc.contributor.authorLam, Wilbur A.
dc.contributor.authorAnderson, Evan J.
dc.contributor.authorWaggoner, Jesse J.
dc.contributor.otherCentro de Estudios y Formación para el Ecodesarrolloes
dc.date.accessioned2026-01-01T22:10:29Z
dc.date.available2026-01-01T22:10:29Z
dc.date.issued2022-11-10
dc.identifier.citationSu, M., Ping, S., Nguyen, P., Rojas, A., Hussaini, L., Registre Carmola, L., Taz, A., Sullivan, J., Martin, G. S., Piantadosi, A., Martinez, M., Lam, W. A., Anderson, E. J., & Waggoner, J. J. (2022). Subgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variants. Open Forum Infectious Diseases, 9(11), Article ofac619. https://doi.org/10.1093/ofid/ofac619en
dc.identifier.otherhttps://doi.org/10.1093/ofid/ofac619es
dc.identifier.urihttp://hdl.handle.net/20.500.14066/4728
dc.descriptionCorrespondence: Jesse J. Waggoner, MD, 1760 Haygood Drive NE, Room E-169, Bay E-1, Atlanta, GA 30322 (jjwaggo@emory.edu).en
dc.description.abstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subgenomic RNA (sgRNA) may indicate actively replicating virus, but sgRNA abundance has not been systematically compared between SARS-CoV-2 variants. sgRNA was quantified in 169 clinical samples by real-time reverse-transcription polymerase chain reaction, demonstrating similar relative abundance among known variants. Thus, sgRNA detection can identify individuals with active viral replication regardless of variant.es
dc.description.sponsorshipConsejo Nacional de Ciencia y Tecnologíaes
dc.format.extent5 páginases
dc.language.isoenges
dc.publisherOxford University Presses
dc.rightsAtribución/Reconocimiento-NoComercial-SinDerivados 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.otherSevere acute respiratory syndrome coronavirus 2es
dc.subject.otherSubgenomic RNAes
dc.subject.otherVariants of concernes
dc.titleSubgenomic RNA abundance relative to total viral RNA among severe acute respiratory syndrome coronavirus 2 variantses
dc.typeinfo:eu-repo/semantics/articlees
dc.typeinfo:eu-repo/semantics/publishedVersiones
dc.identifier.doi10.1093/ofid/ofac619es
dc.description.fundingtextPrograma Paraguayo para el Desarrollo de la Ciencia y Tecnología. Proyectos de investigación y desarrolloes
dc.identifier.essn2328-8957es
dc.issue.number11es
dc.journal.titleOpen Forum Infectious Diseaseses
dc.relation.projectCONACYTPINV20-239es
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.copyright© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.es
dc.volume.number9es


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Except where otherwise noted, this item's license is described as Atribución/Reconocimiento-NoComercial-SinDerivados 4.0 Internacional